Why Some People Have Stronger Vaccine Side Effects, According to the CDC

Estrogen might be the cause for these stronger vaccine side effects in women.

Health experts believe women’s estrogen levels are causing stronger side effects after the COVID-19 vaccination compared to men, according to Healthline. Estrogen is a hormone that helps trigger our body’s immune response to diseases, and it works the same for vaccines.

Conversely, men have higher levels of testosterone, which is expected to have an opposite effect compared to estrogen. Testosterone could contribute to slowing and dampening the immune response to illnesses.

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